Chitooligosaccharides to feed formulation has become one of the directions of the development of new feed, it can improve the disease resistance of the animals, raise chicken breeding rate and meat production rate, increase the rate of the litter size of pig, promote fish growth and reduce death for agricultural biological fertilizer, proliferation of soil and biological bacterial fertilizer bacteria, to enhance the disease resistance of plant, crop disease prevention and control, effectively improve the fruit and vegetable production.